Our center is a referal hospital of the Mediteranian Region and other neighboring Europian Union, Russian Federation and Middle East Countries that provides a comprehensive range of clinical services in radioisotope imaging and therapy. We are equipped with a Position Emission Tomography (PET)/CT scanner with True D technology, two Single Photon Emission Computed Tomography (SPECT) scanners and DEXA for Bone Density Measurement, Ultrasonograpy. We have 4 clinically highly experienced and certified Nuclear Medicine specialist  and highly-trained technicians.

Services Offered:

Radionuclide Therapy Peptide Receptor Radionuclide Therapy (PRRT)

It is a molecular targeted therapy for inoperable metastatic well or moderately differentiated neuroendocrine tumours. It can also be used for other tumours with high somatostatin receptors expression. The treatment is performed with intravenous administration of radioactive somatostatin analogue (e.g. Lutetium-177 or Yttrium-90-labeled radiopeptide).

Radiosynovectomy

It is a radionuclide therapy to treat chronic joint synovitis or synovial processes. The most common main referrals are of chronic inflammatory arthritis e.g. rheumatoid arthritis, and haemophilic synovitis. The treatment is performed by intra-articular injection of the colloidal form of Yttrium-90, Rhenium-186 and Erbium-169.

Iodine-131 MIBG Therapy

It  is a systemically administered radiotherapy used in the treatment of inoperable metastatic neuroectodermal tumours such as pheochromocytoma, paraganglioma, neuroblastoma, medullary thyroid cancer and carcinoid tumors.

Radioiodine Therapy

It is an oral administration of radioactive iodine (iodine-131) for the treatment of thyrotoxicosis (e.g. Graves’ disease, toxic multinodular goiter or toxic adenoma) and differentiated thyroid carcinomas.

Bone Pain Palliative Therapy

Bone-seeking radiopharmaceuticals (e.g. Strontium-89 chloride, Samarium-153, Rhenium-188) are used for the palliation of pain from bone metastasis.

Selective Internal Radiation Therapy (SIRT)

It is a form of local radiation therapy for unresectable liver tumours. The procedure is performed in close coordination with interventional radiologists by delivering radioactive Yttrium-90 microspheres into the arteries supplying the tumours.

Radio-labelled (e.g. , Iodine-131, Yttrium-90)  anti-CD20 monoclonal antibody therapy for refractory or relapsed low-grade non-Hodgkin's lymphoma.

Nuclear Medicine Imaging

Position Emission Tomography (PET)
Advanced imaging technique for oncology, cardiology and neurology. State-of-the-art fusion PET/CT scanner provides functional information with anatomic correlation. Current radiotracers include:

• Fluorine-18 FDG for tumour and infection imaging, to assess myocardial viability and for the work-up of early dementia and refractory epilepsy.
• Gallium-68 DOTA-peptides and analogues for neuroendocrine and other somatostatin receptor positive tumours

Routine Nuclear Medicine Scanning

• Bone scintigraphy for assessment of bone metastases and other skeletal abnormalities. Bone mineral densitometry for assessment of bone mass and evaluation of osteopenia and osteoporosis.
• Brain perfusion imaging for cerebrovascular insufficiency, epilepsy and brain death.
• Gastrointestinal studies (e.g. radionuclide tagged-red blood cells scan, Meckel's scan, hepatobiliary scan, gastric emptying study and peritoneal scan
• Iodine-131 MIBG and Indium-111octreotide imaging for neuroendocrine tumours.
• Parathyroid scintigraphy for localisation of parathyroid adenomas in hyperparathyroidism.
• Lung studies including V/Q scan for pulmonary embolism and lung perfusion scan for lung function quantification prior to surgery.
• Lymphoscintigraphy for lymphoedema.
• Sentinel node scintigraphy and radionuclide occult lesion localisation (ROLL) for breast cancers.
• Labelled white-blood cells scan for infection localisation.
• Nuclear cardiology with myocardial perfusion imaging and radionuclide gated-ventriculography.
• Renal imaging including renography, captopril studies and renal cortical imaging.
• Thyroid scintigraphy for assessment of thyroid nodules and thyroid function.

Non-Imaging Nuclear Medicine Tests

TC99m-DTPA renal clearance study for evaluation of glomerular filtration rate (invivo and invitro test)

Professors/Consultants:

• Prof. Dr. Adil BOZ ( Head of Department)
• Prof. Dr. Metin ERKILIÇ
• Prof. Dr. Binnur KARAYALÇIN
• Assoc. Prof. Dr. Funda AYDIN